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Indications/Uses
Listed in Dosage.
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Dosage/Direction for Use
Adult: PO Adjunct in senile and postmenopausal osteoporosis; Promote constructive anabolism of proteins 5-10 mg/day, increase by 2.5 mg every 2nd or 3rd day.
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Contraindications
In men, prostate or breast carcinoma. Severe hepatic impairment. Hypercalcaemia, hypercalciuria. Pregnancy.
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Special Precautions
Lactation; CV disorders, renal/hepatic impairment, epilepsy, migraine, DM, conditions aggravated by fluid retention. Children. Monitor hepatic function.
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Adverse Reactions
Fluid and electrolyte retention; psychiatric effects; hypercalcaemia, impaired glucose tolerance. Men: Impotence, gynaecomastia, hirsutism, male-pattern baldness, acne, seborrhoea, oedema, cholestatic jaundice. Women: Amenorrhoea, menstrual irregularities. Children: Premature closure of epiphyses, stops linear growth; virilisation symptoms.
Potentially Fatal: Hepatotoxicity. |
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Drug Interactions
May enhance effects of antidiabetics, ciclosporin, levothyroxine, warfarin. Resistance to the effects of neuromuscular blockers may occur.
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CIMS Class
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ATC Classification
D11AE01 - metandienone ; Belongs to the class of topical androgen preparations used in the treatment of dermatological diseases.
A14AA03 - metandienone ; Belongs to the class of androstan derivative anabolic steroids used as systemic anabolic agents. |
