Generic Medicine Info
Indications and Dosage
Differential diagnosis of Wolff-Parkinson-White syndrome, Supraventricular arrhythmias, Ventricular arrhythmias
Adult: 50 mg via IV inj over at least 5 minutes. May also be given by IV infusion, IM inj and oral route.
Digitalis overdosage; complete heart block; lactation; hypersensitivity.
Special Precautions
Incomplete heart block, uncompensated heart failure; myasthenia gravis; elderly; pregnancy. Initiate therapy with extreme caution during acute infections or fever.
Adverse Reactions
Heart block; cardiac arrhythmias; eye twitching; convulsions; resp depression; hepatotoxicity; agranulocytosis.
Potentially Fatal: Coma.
Drug Interactions
Description: Ajmaline directly interferes with depolarization of the cell membrane by blocking the fast inward current of Na into cardiac cells. It slows the rate of change of the depolarization phase of the action potential, moderately prolong the PR, QRS and QT intervals on ECG monitoring. It also has local anesth properties.
MIMS Class
Cardiac Drugs
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