Lixiana

Lixiana

edoxaban

Manufacturer:

Daiichi

Marketer:

Kalbe Farma
Concise Prescribing Info
Contents
Edoxaban
Indications/Uses
Venous thromboembolism eg, DVT & pulmonary embolism. Reduce the risk of stroke in atrial fibrillation.
Dosage/Direction for Use
Venous thromboembolism 30 or 60 mg daily following initial therapy w/ parenteral anticoagulant for 5-10 days. Stroke prevention in atrial fibrillation 30 or 60 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Significant active bleeding, risk for major bleeding, uncontrolled severe HTN. Concomitant use w/ other anticoagulants. Pregnancy & lactation.
Special Precautions
Increased risk of bleeding. Discontinue at least 24 hr prior to surgery. Renal & hepatic impairment. Elderly.
Adverse Reactions
Anemia, epistaxis, GI & oral bleeding, nausea, increased blood bilirubin & γ-glutamyl transferase, headache, abdominal pain.
Drug Interactions
P-glycoprotein inhibitors eg, cyclosporine, dronedarone, erythromycin, ketoconazole.
ATC Classification
B01AF03 - edoxaban ; Belongs to the class of direct factor Xa inhibitors. Used in the treatment of thrombosis.
Presentation/Packing
Form
Lixiana FC tab 30 mg
Packing/Price
28's (Rp675,000/pak)
Form
Lixiana FC tab 15 mg
Packing/Price
10's (Rp675,000/pak)
Form
Lixiana FC tab 60 mg
Packing/Price
28's (Rp675,000/pak)
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