Paget's disease of bone
Adult: As 2nd or 3rd line of treatment: 25 mcg/kg/day by slow infusion for 15 doses followed by 1500 mcg wkly for 2 mth, then every 2 wk for 6 wk.
Hypercalcaemia and hypercalciuria associated with malignancy
Adult: 25 mcg/kg by slow infusion over 4-6 hr. May be repeated several times at intervals of 24-72 hr.