Adults: Recommended Dose: 1200 mg/day divided into 3-4 single administrations. Should gastric disturbances appear after ingestion of Spedifen, then the administration can be performed by drinking concomitantly some milk or during meals.
Rheumatoid Arthritis: A higher dosage may be required but in any case, it is recommended not to exceed ibuprofen 2400 mg/day, by considering that the lowest possible effective dose is to be administered.
Primary Dysmenorrhea: Recommended Dose: 400 mg every 4 hrs until pain relief, always considering the lowest possible effective dosage.
Elderly: The dosage is to be established by the physician, as a possible usual dose reduction may be needed.
Kidney Failure: Dosage must be adequately adjusted, being the drug eliminated preferably through renal excretion.