Not recommended in primary aldosteronism & dual blockade of the renin-angiotensin-aldosterone system. Bilateral renal artery stenosis or artery stenosis to single functioning kidney; hyperkalaemia; aortic or mitral valve stenosis or obstructive hypertrophic cardiomyopathy; ischaemic cardiopathy or CV disease. Correct vol &/or Na depletion prior to initiation. Periodic monitoring of serum K & creatinine levels, electrolytes & BP. Not recommended in combination w/ ACE inhibitors; lithium. Black patients. May affect ability to drive & use machines. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Not recommended during 1st trimester of pregnancy & lactation. Childn 0-18 yr.