Ceflour

Ceflour

cefuroxime

Manufacturer:

Y.S.P. Industries

Distributor:

Y.S.P. Industries
Concise Prescribing Info
Contents
Cefuroxime (tab: axetil; vial: Na)
Indications/Uses
Upper & lower resp tract, GUT, ENT, skin & soft tissue, bone & joint infections, UTI, O&G infections, septicaemia, meningitis, peritonitis, gonorrhoea. Surgical prophylaxis.
Dosage/Direction for Use
Tab Usual duration: 7 days (range: 5-10 days). Adult & adolescent >13 yr Most infections 250 mg bd. Mild to moderate lower resp tract infection eg, bronchitis 250 mg bd. More severe lower resp tract infections eg, pneumonia 500 mg bd. UTI 125 mg bd. Pyelonephritis 250 mg bd. Gonorrhoea 1 g as single dose. Childn Usual dose: 125 mg bd. Acute otitis media Childn >2 yr 250 mg bd. IM/IV inj Adult 0.75 g 8 hrly. Severe, complicated infections 1.5 g 6-8 hrly. Bacterial meningitis Max: 3 g 8 hrly. Uncomplicated gonorrhoea 1.5 g IM as single dose at 2 separate sites w/ oral probenecid 1 g. Surgical prophylaxis 1.5 g pre-op & 0.75 g IV/IM 8 hrly. Prophylaxis in open heart surgery 1.5 g IV at anaesth induction & 12 hrly thereafter for total: 6 g. Infant & childn >3 mth 50-100 mg/kg daily in divided doses 6-8 hrly. More severe infection 100 mg/kg daily. Bacterial meningitis Initially 200-240 mg/kg daily IV in divided doses 6-8 hrly.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
Hypersensitivity to β-lactams. History of GI disease especially colitis. Pseudomembranous colitis. Prolonged use. Renal impairment. Pregnancy & lactation.
Adverse Reactions
Headache, dizziness, GI disturbances, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic reactions, rash, urticaria, pruritus, hematologic & hepatic effects, transient pain at inj site, thrombophlebitis, fever & anaphylaxis.
Drug Interactions
Anticoagulants, heparin or thrombolytic agents. NSAIDs, salicylates or sulfapyrazone, potent diuretics. Decreased renal tubular excretion by probenecid. Antacids.
MIMS Class
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Ceflour FC tab 250 mg
Packing/Price
10 × 10's
Form
Ceflour powd for inj 0.75 g
Packing/Price
50 × 1's
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