Ceftezole


Concise Prescribing Info
Indications/Uses
Susceptible infections.
Dosage/Direction for Use
Adult : IM 2-4 g/day in 2-3 divided doses.
Dosage Details
Intramuscular
Susceptible infections
Adult: 2-4 g daily in 2-3 divided doses.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
Hypersensitivity to penicillins; renal impairment; porphyria. Monitor renal and haematological status.
Adverse Reactions
Nausea; vomiting; diarrhea; hypersensitivity reactions; nephrotoxicity; convulsions; CNS toxicity; hepatic dysfunction; hematologic disorders; pain at injection site (IM); thrombophlebitis (IV infusion); superinfection with prolonged use.
Potentially Fatal: Pseudomembranous colitis.
Drug Interactions
Renal excretion inhibited by probenecid. Bacteriostatic antibacterials.
Potentially Fatal: Nephrotoxic drug eg. aminoglycoside may increase risk of kidney damage. Enhanced nephrotoxicity with a loop diuretic.
Lab Interference
Positive direct antiglobulin Coombs' test; falsely high values w/ Jaffe method of measuring creatinine conc; +ve reactions for false glucose using copper-reduction reactions; transient increases in liver enzyme values.
Action
Description: Ceftezole has properties similar to cefalotin. It is active against S. aureus, S. pneumoniae, E. coli, Proteus mirabilis.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Ceftezole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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