FC tab Resp tract infection & complicated UTI 250-500 mg bd.
Acute, uncomplicated UTI 125 mg bd or 250 mg once-bd.
Cystitis in premenopausal women & acute, uncomplicated gonorrhea 250 mg as single dose for 1 day.
Extragenital gonorrhea 125 mg bd.
Diarrhea 500 mg once-bd.
Other infections 500 mg bd.
Severe, life-threatening infections eg, Strep pneumonia, recurrent cystic fibrosis infection, bone & joint infections, septicemia, peritonitis (Pseudomonas, Staph or Strep is present) 750 mg bd.
Renal impairment & continuous ambulatory peritoneal dialysis 500 mg once daily or 250 mg bd.
CrCl 31-60 mL/min/1.73 m2 Max: 1,000 mg daily,
30-50 mL/min 250-500 mg every 12 hr,
<30 mL/min/1.73 m2 Max: 500 mg daily,
5-29 mL/min 250-500 mg every 18 hr.
Hemodialysis or peritoneal dialysis patient 250-500 mg every 24 hr (after dialysis).
Infusion Resp tract infection 200-400 mg bd.
Acute, uncomplicated UTI & extragenital gonorrhea 100 mg bd.
Cystitis in premenopausal women & acute, uncomplicated gonorrhea 100 mg as single dose for 1 day.
Complicated UTI, diarrhea & other infections 200 mg bd.
Severe, life-threatening infections eg, Strep pneumonia, recurrent cystic fibrosis infections, bone & joint infections, septicemia, peritonitis (Pseudomonas, Staph, Strep is present) 400 mg tds.
CrCl 31-60 mL/min/1.73 m2 Max: 800 mg IV daily,
<30 mL/min/1.73 m2 Max: 400 mg IV daily. Duration:
Kidney, urinary tract & abdominal cavity infections Up to 7 days.
Patient w/ weakened body defenses Over the entire period of neutropenic phase.
Osteomyelitis Max: 2 mth.
All other infections 7-14 days.
Strep infections At least 10 days.
Chlamydia infection Min: 10 days.