Hypersensitivity to amide-type local anaesth, methylparaben, its metabolite or PABA. Inflammation &/or sepsis in the inj region &/or septicaemia. Stokes-Adams syndrome, Wolff-Parkinson-White syndrome, severe degrees of SA, AV or intraventricular block in absence of artificial pacemaker.
Acute CNS & CV toxic effects. Constantly monitor CV, resp vital signs & consciousness. 2nd or 3rd degree AV block, severe hepatic disease, severe renal impairment, concomitant class III antiarrhythmics (eg, amiodarone). Epilepsy, impaired cardiac conduction, bradycardia, severe shock or digitalis intoxication, impaired CV function. Acute porphyria. May impair ability to drive or operate machinery. Pregnancy & lactation. Elderly, young or debilitated patients.