Hypersensitivity. Long-term effects in acute myeloid leukaemia (AML). Not to be used in myelodysplastic syndrome, chronic myelogenous leukemia & secondary AML. De novo
AML patients <55 yr; recent history of pulmonary infiltrates or pneumonia; glumerulonephritis; sickle cell trait or disease. Immunogenicity; aortitis. Monitor for preliminary signs of acute resp distress syndrome; urinalysis. Closely monitor patients who develop capillary leak syndrome & spleen size. Regularly monitor platelet count & hematocrit. Regularly perform WBC count. May cause allergic reactions due to latex. Mobilisation of blood progenitor cells in patients or healthy donors. High-dose use. Fructose intolerance. Women of childbearing potential should use effective contraception. Not recommended during pregnancy. Lactation. Childn.