Paramethasone


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Anti-inflammatory 2-24 mg/day. Allergic conditions W/ chlorphenamine maleate: 1 mg 3 times/day. Up to 6 mg/24 hr.
Dosage Details
Oral
Allergic conditions
Adult: As acetate, with chlorphenamine maleate: 1 mg tid, may increase up to 6 mg in 24 hr.
Child: As acetate, with chlorphenamine maleate: 6-14 yr: 0.5 mg 3 to 4 times a day; max: 4 mg/day.

Oral
Anti-inflammatory
Adult: 2-24 mg/day
Contraindications
Tuberculosis, fungal infection, herpes, bone disease, thyroid disease, colitis, peptic ulcer, diabetes, myasthenia gravis, liver or kidney disease, diverticulitis, glaucoma, heart disease. Pregnancy.
Special Precautions
Elderly, children, lactation. Avoid abrupt discontinuation, immunisation. Monitor growth in children.
Adverse Reactions
Acne, poor wound healing, indigestion, nausea, vomiting, thirst, constipation, gaseousness, unpleasant taste, diarrhoea, headache, cough, dizziness, hoarseness, appetite gain or loss. Prolonged use: growth retardation in children, glaucoma, cataracts, diabetes, fragile bones, thin skin, functional dependence.
Potentially Fatal: Anaphylaxis.
Overdosage
Headache, convulsions, heart failure.
Drug Interactions
Decreased effects with anticonvulsants, antihistamine, barbiturates, chloral hydrate, ephedrine, rifampin. Increased effects with NSAID, contraceptives, indomethacin, tobacco. Decreases effects of anticoagulants, antidiabetics, cholinergics, insulin, isoniazid, salicylates, potassium. Increases effects of theophylline. Increased risk of hypokalemia with amphotericin, chlorthalidone, thiazide diuretics, furosemide, digitalis preparations (possible digitalis toxicity). Increased risk of stomach ulcers with alcohol.
Action
Description: Paramethasone is a corticosteroid, used systemically for its glucocorticoid activity. 2 mg paramethasone is equivalent in anti-inflammatory activity to 5 mg prednisolone.
Disclaimer: This information is independently developed by MIMS based on Paramethasone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in