Generic Medicine Info
Indications and Dosage
Hypercholesterolaemia, Hyperlipoproteinaemia
Adult: 500 mg bid.
Should be taken with food.
Child <2 yr.
Special Precautions
Recent myocardial damage, severe ventricular arrhythmias, CV-associated syncope, prolonged QT interval, hypokalaemia, pregnancy, lactation.
Adverse Reactions
GI upsets; diarrhoea; flatulence; abdominal pain; nausea; vomiting. Hypersensitivity reactions such as angioedema.
Potentially Fatal: Fatal cardiac arrhythmias.
Drug Interactions
Increased risk of arrhythmias with tricyclic antidepressants, class I or III antiarrhythmics, phenothiazines or drugs that prolong QT interval. Reduced plasma concentrations of ciclosporin when used concurrently.
Description: Probucol is a lipid-regulating drug that lowers total plasma-cholesterol concentrations, mainly by reducing low-density-lipoprotein and high-density lipoprotein cholesterol.
Absorption: Limited and variable.
Excretion: Mainly by the biliary system into the faeces.
MIMS Class
Dyslipidaemic Agents
Disclaimer: This information is independently developed by MIMS based on Probucol from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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