Shinadex Dosage & Drug Information

Concise Prescribing Info

Contents

Per mL Chloramphenicol 5 mg, dexamethasone Na phosphate 1 mg

Indications/Uses

Acute & chronic keratitis & conjuctivitis of an infectious, allergic but nonviral nature. Anterior uvea infections (iritis, iridocyclitis). Skleritis, episcleritis & myositis. Sympathic ophthalmia. Post-op management of cataract, glaucoma & strabismus.

Dosage/Direction for Use

Instill 1 drop into conjunctival sac 3-5 times daily for up to 10 days. Acute case Up to 1 drop/hr.

Contraindications

Hypersensitivity. Corneal lesions due to non-bacterial infections & ulcerative processes. Herpes simplex & other viral infections. Mycosis & other fungal infections. Severe blood disorders due to bone marrow depression & hepatic dysfunction. Family history of bone marrow depression. Pregnancy & lactation.

Special Precautions

Corticosteroids may mask, activate or aggravate eye infection. Local use of dexamethasone over prolonged period may lead in some cases to secondary glaucoma & development of complicated cataract. Possibility of inducing corneal abscess, fungal keratopathy or glaucoma. Childn.

Adverse Reactions

Itching, redness, swelling, foreign body sensation or other sign of irritation not present before therapy. Ocular burning or stinging upon drug instillation & blurred vision, elevation of IOP, posterior subcapsular cataract formation, secondary ocular infection following suppression of host response; delayed wound healing & corneal thinning &/or globe perforation may occur. Ptosis & mydriasis. Dysgeusia.

View ADR Monitoring Form

Drug Interactions

Penicillins, cephalosporins, gentamicin, tetracyclines, polymyxin B, vancomycin or sulfadiazine, drugs having adverse effect on hematopoiesis, sulfonylureas, coumarin derivatives, hydantoins, MTX.

MIMS Class

Eye Antiseptics with Corticosteroids

ATC Classification

S01CA01 - dexamethasone and antiinfectives ; Belongs to the class of corticosteroids in combination with antiinfectives. Used in the treatment of eye diseases.

Regulatory Classification

Presentation/Packing

Form

Shinadex eye drops

Packing/Price

5 mL x 10 × 1's;5 mL x 12 × 1's;5 mL x 20 × 1's;5 mL x 24 × 1's

Shinadex

Manufacturer:

Y.S.P. Industries

Distributor:

Y.S.P. Industries