Hypersensitivity. Transient worsening of heart failure or fluid retention. Low BP (systolic BP <100 mmHg), ischemic heart disease, diffuse vascular disease, COPD, bronchospasm, DM, peripheral vascular disease, Raynaud's phenomenon, thyrotoxicosis, bradycardia, psoriasis, pheochromocytoma. Prinzmetal's variant angina. Patients undergoing general surgery. Contact lens wearers. Avoid abrupt w/drawal. Combination w/ digitalis glycosides. Concomitant use w/ verapamil- or diltiazem-type Ca-channel blockers, other antiarrhythmics, anesth. May affect ability to drive or operate machinery. Underlying renal insufficiency. Pregnancy. Not recommended during lactation. Childn <18 yr.