Valethamate


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Dysmenorrhoea; GI tract spasm; Post-op pain; Tenesmus; Urinary tract and bile stone colic; Visceral spasms Per tab contains valethamate bromide 10 mg and paracetamol 325 mg: 1 tab 3 times/day. IV/IM Dysmenorrhoea; GI tract spasm; Urinary tract and bile stone colic; Visceral spasms 8-16 mg/day.
Dosage Details
Oral
Dysmenorrhoea, Gastrointestinal tract spasm, Postoperative pain, Tenesmus, Urinary tract and bile stone colic, Visceral spasms
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.

Parenteral
Dysmenorrhoea, Gastrointestinal tract spasm, Urinary tract and bile stone colic, Visceral spasms
Adult: 8-16 mg daily, via IM or IV inj.
Contraindications
Narrow angle glaucoma, benign prostatic hyperplasia, paralytic ileus, pyloric stenosis, ulcerative colitis, megacolon, tachyarrhythmia. Severe hepatic and renal impairment.
Special Precautions
May impair ability to drive or operate machinery at high doses.
Adverse Reactions
Dry mouth, blurring of vision, difficulty in swallowing and talking, constipation, urinary retention, mydriasis, arrhythmias.
Drug Interactions
Increased antimuscarinic side effects with drugs with antimuscarinic properties e.g. amantadine, antihistamines, phenothiazide antipsychotics, TCAs. Antagonise GI effects of domperidone, metoclopramide. Delayed gastric emptying reduces absorption of other drugs.
Action
Description: A quaternary ammonium anticholinergic with peripheral actions close to those of atropine.
Storage
Store below 25°C.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Valethamate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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