Azithrom

Azithrom

azithromycin

Manufacturer:

NingboTisun Medic

Distributor:

2 World Traders
Concise Prescribing Info
Contents
Azithromycin
Indications/Uses
Resp tract infections including otitis media, skin & soft-tissue infections & uncomplicated genital infections. Prophylaxis & as a component in the treatment regimen of Mycobacterium avium complex (MAC). Prophylaxis of endocarditis in at risk patient unable to take penicillin. Management of trachoma & typhoid.
Dosage/Direction for Use
Adult 500 mg as a single daily dose for 3 days or initially 500 mg followed by 250 mg daily for a further 4 days. Chancroid & uncomplicated genital infections caused by Chlamydia trachomatis 1 g as a single dose. Uncomplicated gonorrhea 2 g as a single dose. Granuloma inguinale Initially 1 g followed by 500 mg daily or 1 g once wkly for at least 3 wk. Prophylaxis of disseminated MAC infections 1.2 g once wkly. Treatment or secondary prophylaxis of other antimycobacterial infections 500 mg once daily.
Administration
May be taken with or without food: May be taken w/ meals to reduce GI discomfort. Swallow whole.
Contraindications
Hypersensitivity to azithromycin, erythromycin & ketolide antibiotics.
Special Precautions
May cause longer QT intervals. Hepatic & renal impairment.
Adverse Reactions
GI disturbances. Headache, somnolence, taste disturbance.
Drug Interactions
May reduce the rate of absorption w/ antacid containing Al or Mg salts. Increased conc w/ nelfinavir. Theoretical possibility of ergotism w/ ergotamine derivatives. Possibility of increased digoxin levels. Elevated cyclosporine Cmax & AUC0-5. Increased phosphorylated zidovudine conc. Enhanced effect of astemizole, alfentanil. May increase QT interval prolongation, ventricular arrhythmias & Torsades de pointes w/ cisapride.
MIMS Class
ATC Classification
J01FA10 - azithromycin ; Belongs to the class of macrolides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Azithrom FC tab 500 mg
Packing/Price
3's
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