Carvid

Carvid

carvedilol

Manufacturer:

Therapharma

Distributor:

Therapharma
Concise Prescribing Info
Contents
Carvedilol
Indications/Uses
Management of HTN & angina pectoris.
Dosage/Direction for Use
HTN Initially 12.5 mg once daily or 6.25 mg bid, may be increased at 2-wk intervals. Max: 50 mg. Angina pectoris Initially 12.5 mg bid for 2 days then increase to 25 mg bid. Dose may be increased at 2-wk intervals. Max: 100 mg bid. CHF Initially 3.125 mg bid for 2 wk. If dose is tolerated, increase to 6.25 mg bid, followed by 12.5 mg bid & thereafter 25 mg bid at 2-wk intervals. Mild to moderate heart failure in patients >85 kg Max: 50 mg bid. Severe heart failure & mild to moderate heart failure in patient <85 kg Max: 25 mg bid. Left ventricular dysfunction following MI Initially 6.25 mg, then increase to bid & maintain for 3-10 days. Decrease dose to 3.125 mg bid if patient develop signs of tolerance. Max: 25 mg bid.
Administration
Should be taken with food.
Contraindications
Unstable/decompensated heart failure, clinically manifest hepatic impairment, marked fluid retention or overload requiring IV inotropic support, 2nd- or 3rd-degree AV block, severe bradycardia or hypotension, sick sinus syndrome, cardiogenic shock, metabolic acidosis, history of bronchospasm or asthma, other obstructive lung disorders.
Special Precautions
Diabetes & hypoglycemia, peripheral vascular disease, thyrotoxicosis, pheochromocytoma, Raynaud's phenomenon, psoriasis, Prinzmetal's variant angina. Pregnancy & lactation. Childn.
Adverse Reactions
Diarrhea, nausea, dizziness, abnormal or blurred vision.
Drug Interactions
CYP2D6 inhibitors, catecholamine-depleting agents, clonidine, ciclosporin, digoxin, Ca channel blockers, insulin or oral hypoglycemics, amiodarone, anesth, other β-blockers.
MIMS Class
Beta-Blockers
ATC Classification
C07AG02 - carvedilol ; Belongs to the class of alpha and beta blocking agents. Used in the treatment of cardiovascular diseases.
Presentation/Packing
Form
Carvid tab 25 mg
Packing/Price
30's (P558.33/pack)
Form
Carvid tab 6.25 mg
Packing/Price
30's (P335/pack)
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