Tergecef/Tergecef OD

Tergecef/Tergecef OD

cefixime

Manufacturer:

Asian Antibiotics

Distributor:

Westmont

Marketer:

UNILAB, Inc
Concise Prescribing Info
Contents
Cefixime
Indications/Uses
Acute bronchitis, acute exacerbations of chronic bronchitis, bronchiectasis w/ infection, secondary infections in chronic resp tract diseases, pneumonia; UTI including pyelonephritis & cystitis; gonococcal urethritis; cholecystitis, cholangitis; scarlet fever; sinusitis, tonsillitis, pharyngitis, otitis media; typhoid fever (enteric fever) including multi-drug resistant typhoid fever.
Dosage/Direction for Use
Adult Uncomplicated cervical/urethral gonococcal infections 400 mg single dose. Uncomplicated UTI 100 mg bid or 200 mg once daily for 7-14 days. Uncomplicated cystitis 200 mg bid or 400 mg once daily for 3 days. Uncomplicated acute pyelonephritis 200 mg bid or 400 mg once daily for 14 days. Typhoid fever 200 mg bid or 400 mg once daily for 7-1 days. Cap Adult & childn >12 yr (>50 kg) 400 mg once daily or 200 mg every 12 hr for 7-14 days. Childn 7-12 yr 200-300 mg once daily or 100 mg every 12 hr for 7-14 days.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to cefixime, other cephalosporins or penicillins.
Special Precautions
Serious acute hypersensitivity reactions. Clostridium difficile-associated diarrhea & colitis. Fall in prothrombin activity. Overgrowth of non-susceptible organisms including fungi on long-term or repeated use. False +ve direct Coombs' test; ketones in the urine using nitroprusside test & glucose in the urine using Clinitest, Benedict's soln or Fehling's soln. Pregnancy & lactation. Childn <6 mth.
Adverse Reactions
Anaphylactic/anaphylactoid reactions, skin rashes, urticaria, fever, pruritus, arthralgia, angioedema, facial edema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, serum sickness-like reactions; diarrhea, loose or frequent stools, abdominal pain, anorexia, flatulence, dry mouth, dyspepsia, nausea, vomiting, pseudomembranous colitis; transient elevation of ALT, AST, alkaline phosphatase, hepatitis, jaundice; transient elevations in BUN or creatinine levels; headache, dizziness, nervousness, insomnia, somnolence, malaise, fatigue, seizures; transient thrombocytopenia, leukopenia, neutropenia, eosinophilia; hyperbilirubinemia.
Drug Interactions
Elevated carbamazepine levels. Increased prothrombin time w/ or w/o clinical bleeding w/ warfarin & other anticoagulants. Increased peak serum conc & AUC w/ probenecid. Decreased peak serum conc & AUC w/ aspirin.
MIMS Class
ATC Classification
J01DD08 - cefixime ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Tergecef OD cap
Packing/Price
30's
Form
Tergecef cap 100 mg
Packing/Price
50's (P3,929.67/pack)
Form
Tergecef cap 200 mg
Packing/Price
30's (P3,888.48/pack)
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