Dipivefrine


Generic Medicine Info
Indications and Dosage
Ophthalmic
Ocular hypertension, Open-angle glaucoma
Adult: As hydrochloride: Instil 1 drop of 0.1% soln in the eye/s every 12 hr.
Contraindications
Hypersensitivity. Patients with narrow angles, since any pupillary dilatation may cause an attack of angle-closure glaucoma.
Special Precautions
Aphakic patients; lactation.
Adverse Reactions
Ocular hyperaemia, burning, stinging, irritation, follicular conjunctivitis, mydriasis, allergic reactions, adrenochrome deposits in the conjunctiva and cornea, headache, browache and eye pain. Very rarely, tachycardia and hypertension may occur.
Potentially Fatal: Generally well tolerated. Side effects fewer when compared to epinephrine drops.
Drug Interactions
Additive ocular hypotensive effects with other anti-glaucoma drugs.
Action
Description: Dipivefrine is a prodrug of adrenaline. It reduces IOP by decreasing aqueous production and by enhancing outflow.
Disclaimer: This information is independently developed by MIMS based on Dipivefrine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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