Initially 5 mg once daily. Mild to moderate Alzheimer disease 5 or 10 mg once daily. Moderate to severe Alzheimer disease 10 or 23 mg once daily. A dose of 10 mg should not be achieved until the patient have been on a daily dose of 5 mg for 4-6 wk.
Bradycardia or heart block may occur in patients w/ & w/o known underlying cardiac conduction abnormalities. Monitor patients for symptoms of active or occult GI bleeding, especially patients at risk of developing ulcers eg, patients w/ history of ulcer disease or receiving concurrent NSAIDs. History of asthma or obstructive pulmonary disease. Pregnancy & lactation. Childn.