Moduretic

Moduretic

Manufacturer:

M & H Manufacturing

Distributor:

B L Hua
Concise Prescribing Info
Contents
Amiloride HCl 5 mg, hydrochlorothiazide 50 mg
Indications/Uses
Suspected or anticipated K depletion. Minimizes the possibility or the development of excessive K loss in patients during vigorous diuresis for prolonged periods. Conditions where the positive effect on K balance is particularly important. Used alone or as an adjunct to other antihypertensive drugs in conditions eg, HTN, edema of cardiac origin, & hepatic cirrhosis w/ ascites & edema.
Dosage/Direction for Use
HTN 1-2 tab once daily or in divided doses. Edema of cardiac origin Initially 1-2 tab daily. Hepatic cirrhosis w/ ascites 1 tab daily. Max: 4 tab daily.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to other sulfonamide-derived drugs. Hyperkalemia, other concomitant antikaliuretic therapy or K supplementation, renal insufficiency. Pregnancy & lactation. Childn.
Special Precautions
Patients w/ impaired hepatic & renal function, monitor for signs of fluid & electrolyte imbalance. May impair glucose tolerance, cause hyperkalemia or hypokalemia, or precipitate hyperuricemia &/or gout. Increase in cholesterol & triglycerides. Azotemia & oliguria (discontinue). Possibility of exacerbation or activation of SLE.
Adverse Reactions
Headache, weakness, nausea, anorexia, dizziness.
Drug Interactions
Potentiate orthostatic hypotension w/ alcohol, barbiturates, narcotics. Additive effect w/ other antihypertensives. Intensified electrolyte depletion w/ corticosteroids, ACTH. Thiazides, antidiabetic drugs, pressor amines, skeletal muscle relaxants, nondepolarizing drugs, lithium, NSAIDs.
MIMS Class
ATC Classification
C03EA01 - hydrochlorothiazide and potassium-sparing agents ; Belongs to the class of low-ceiling diuretics in combination with potassium-sparing agents. Used as diuretics.
Presentation/Packing
Form
Moduretic tab
Packing/Price
50 × 10's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in