Concise Prescribing Info
Urinary retention.
Dosage/Direction for Use
Adult : PO 10-50 mg 3-4 times/day.
Dosage Details
Urinary retention
Adult: 10-50 mg 3-4 times daily.
Should be taken on an empty stomach. Take 1 hr before or 2 hr after meals.
Intestinal or urinary obstruction, recent MI, pronounced bradycardia or hypotension, recent intestinal anastomosis, hyperthyroidism, peptic ulcer, latent or active bronchial asthma, vasomotor instability, coronary artery disease, epilepsy, parkinsonism. Lactation.
Special Precautions
Adverse Reactions
Nausea, vomiting, sweating, intestinal colic, malaise, abdominal cramps or discomfort, belching, diarrhoea, borborygmi, salivation, urinary urgency, headache, hypotension, vasomotor response, hot flushes, sweating, lachrymation, miosis, seizure, reflux infection.
Parenteral/PO/SC: C
Patient Counseling Information
May impair ability to drive or operate machinery.
Assess bladder and sphincter adequacy prior to therapy.
Symptoms: Nausea, salivation, lachrymation, eructation, involuntary defecation and urination, transient dyspnoea, palpitation, bradycardia, peripheral vasodilation leading to HTN, transient heart block and feeling of constriction under sternum. Management: Perform gastric lavage and aspiration. Administer atropine sulfate 1-2 mg IV, IM or SC 2-4 hrly as necessary, to control muscarinic effects. Supportive treatment may include IV diazepam 5-10 mg; tubocurarine (w/ assisted respiration, to control muscle twitching); oxygen may be required.
Drug Interactions
Atropine, quinidine, procainamide, epinephrine and other sympathomimetic amines may antagonise the effect of bethanechol. Critical fall in blood pressure, usually preceded by severe abdominal symptoms, may occur when used w/ ganglionic blocking agents. Additive effects and increased toxicity w/ other cholinergic drugs or anticholinesterase agents (e.g. neostigmine).
Description: Bethanechol acts primarily by stimulating parasympathetic nervous system, hence releasing acetylcholine at the nerve endings. It increases the tone of detrusor urinae muscle, producing a contraction to initiate urination. It also stimulates gastric motility, restores impaired rhythmic peristalsis and increases gastric tone.
Onset: 30-90 min.
Duration: Approx 1 hr.
Absorption: Poorly absorbed from the GI tract.
Chemical Structure

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Store between 20-25°C.
ATC Classification
N07AB02 - bethanechol ; Belongs to the class of choline esters. Used as parasympathomimetics.
Disclaimer: This information is independently developed by MIMS based on Bethanechol from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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