1st treatment should be given in a medical institution or under physician's guidance for patients who have never received Firazyr previously. Patients w/ laryngeal attacks; acute ischemic heart disease or unstable angina pectoris; history of or recent stroke. Minor influence on the ability to drive & use machines. Breastfeeding women should not breastfeed for 12 hr after treatment. Pregnancy. Childn <2 yr or weighing <12 kg. Elderly >65 yr.