Irprestan

Irprestan

irbesartan

Manufacturer:

Teva

Distributor:

Zuellig
Concise Prescribing Info
Contents
Irbesartan
Indications/Uses
Treatment of essential HTN, renal disease in patients w/ HTN & type 2 DM.
Dosage/Direction for Use
Adult Initial & maintenance dose: 150 mg once daily. Hypertensive type 2 diabetics Initially 150 mg once daily. May be titrated up to 300 mg once daily.  Elderly Initially 75 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Concomitant use w/ aliskiren-containing products in patients w/ DM or renal impairment (GFR <60 mL/min/1.73 m2). Pregnancy (2nd & 3rd trimesters).
Special Precautions
Intravascular vol depletion should be corrected prior to initiation of treatment. Renovascular HTN. Periodic monitoring of serum K & creatinine levels in renally impaired & kidney transplant patients. Hypertensive patients w/ type 2 DM & renal disease. Concomitant w/ lithium. Aortic & mitral valve stenosis, obstructive hypertrophic cardiomyopathy. Primary aldosteronism. Dual blockade of the renin-angiotensin-aldosterone system (RAAS) through the combined use of ACE inhibitors, angiotensin II receptor blockers or aliskiren is not recommended. ACE inhibitors & angiotensin II receptor blockers should not be used concomitantly in patients w/ diabetic nephropathy. May affect ability to drive or operate machinery. Lactation. Childn & adolescents.
Adverse Reactions
Hyperkalaemia, dizziness, orthostatic dizziness, nausea, vomiting, musculoskeletal pain, orthostatic hypotension, fatigue. Increased plasma creatinine kinase levels.
Drug Interactions
Diuretics & other antihypertensives, K supplements & K-sparing diuretics, lithium, NSAIDs. Higher frequency of adverse events w/ combined use of ACE inhibitors, angiotensin II receptor blockers, or aliskiren.
ATC Classification
C09CA04 - irbesartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Irprestan FC tab 300 mg
Packing/Price
28's
Form
Irprestan FC tab 150 mg
Packing/Price
28's
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