Romiplate

Romiplate

romiplostim

Manufacturer:

Kyowa Kirin

Distributor:

DCH Auriga - Healthcare
/
Four Star
Concise Prescribing Info
Contents
Romiplostim
Indications/Uses
Adult chronic immune (idiopathic) thrombocytopenic purpura in splenectomised patients who are refractory to other treatments (eg, corticosteroids & Ig). 2nd-line treatment for adult non-splenectomised patients to whom surgery is contraindicated.
Dosage/Direction for Use
SC inj Initially 1 mcg/kg once wkly, may be increased by increments of 1 mcg/kg until platelet count ≥50 x 109/L is achieved. Max: 10 mcg/kg once wkly.
Contraindications
Hypersensitivity to romiplostim or E. coli-derived proteins.
Special Precautions
Recurrence of thrombocytopenia & bleeding after discontinuation. Increased bone marrow reticulin. Thrombotic/thromboembolic complications. Progression of existing myelodysplastic syndrome. Immunogenicity. Alterations in RBC & WBC. May impair ability to drive or operate machinery. Renal & hepatic impairment. Pregnancy & lactation. Childn <18 yr.
Adverse Reactions
Hypersensitivity reactions, headache. Reoccurrence of thrombocytopenia & bleeding after cessation of treatment, increased bone marrow reticulin, thrombotic/thromboembolic complications, progression of existing myelodysplastic syndrome to acute myeloid leukemia.
MIMS Class
ATC Classification
B02BX04 - romiplostim ; Belongs to the class of other systemic hemostatics. Used in the treatment of hemorrhage.
Presentation/Packing
Form
Romiplate powd for soln for inj 250 mcg
Packing/Price
1's
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