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Indications/Uses
HTN.
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Dosage/Direction for Use
Adult: PO Initial: 5-10 mg once daily. Maintenance: 10-20 mg once daily.
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Administration
May be taken with or without food.
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Contraindications
Cardiogenic shock; recent MI or acute unstable angina; severe aortic stenosis.
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Special Precautions
Hypotension, poor cardiac reserve, heart failure. Sudden withdrawal may exacerbate angina. Discontinue in patients who experience ischaemic pain following admin. Pregnancy, lactation.
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Adverse Reactions
Dizziness; flushing; headache; hypotension; peripheral oedema; tachycardia; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression; ischaemic chest pain; cerebral or myocardial ischaemia; transient blindness; rashes; fever; abnormal liver function; gingival hyperplasia; myalgia; tremor; impotence.
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Drug Interactions
Other antihypertensives; aldesleukin; antipsychotics that cause hypotension; may modify insulin and glucose responses; quinidine; carbamazepine; phenytoin; rifampicin; cimetidine; erythromycin.
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CIMS Class
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ATC Classification
C08CA12 - barnidipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
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