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Indications/Uses
Listed in Dosage.
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Dosage/Direction for Use
Adult: PO HTN Initial: 10 mg once daily. Maintenance: 20-40 mg/day as a single or in 2 divided doses. Max: 80 mg/day. Heart failure Initial: 2.5 mg once daily. Max: 20 mg/day.
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Administration
May be taken with or without food.
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Contraindications
History of angioedema due to previous ACE inhibitor treatment. Pregnancy.
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Special Precautions
Patients w/ diarrhoea, severe volume and/or salt depletion, unilateral or bilateral renal artery stenosis. Patients on dietary salt restriction and dialysis. Increased risk of angioedema in black patients. Renal impairment. Lactation. Patient Counselling May impair ability to drive and operate machinery. Monitoring Parameters Monitor BP. Periodic monitoring of serum creatinine, and K levels.
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Adverse Reactions
Headache, dizziness, fatigue, persistent and non productive cough, somnolence, nausea, transient elevations in BUN and serum creatinine, hyperkalaemia. Intestinal angioedema.
Potentially Fatal: Anaphylactoid reactions and angioedema. Cholestatic jaundice which may progress to fulminant hepatic necrosis. |
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Drug Interactions
Additive hyperkalaemic effects w/ K-sparing diuretics, K supplements, other drugs that can cause hyperkalaemia. May increase lithium concentration and toxicity.
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CIMS Class
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ATC Classification
C09AA07 - benazepril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
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