Cilazapril


Generic Medicine Info
Administration
May be taken with or without food.
Contraindications
History of angioedema w/ previous ACE inhibitor therapy. Hereditary and idiopathic angioedema. Ascites. Severe renal impairment. Coadministration w/ aliskiren in patients w/ DM or renal impairment. Pregnancy.
Special Precautions
Patients w/ aortic stenosis or outflow tract obstruction, ishaemic heart or cerebrovascular disease, unilateral or bilateral renal artery stenosis, and collagen vascular disease. Hepatic and renal impairment. Elderly, lactation. Patient Counselling May impair ability to drive and operate machineries. Monitoring Parameters Monitor serum creatinine, BUN, electrolytes, CBC w/ differential and BP.
Adverse Reactions
Dizziness, headache, fatigue, persistent dry cough, skin rash, nausea, hyperkalaemia, symptomatic hypotension.
Potentially Fatal: Anaphylactic reactions, fulminant hepatic necrosis.
Drug Interactions
Additive hyperkalaemic effects w/ K-sparing diuretics, K supplements, other drugs that can cause hyperkalaemia. May increase lithium concentration and toxicity. Concomitant use w/ TCAs and antipsychotics may further reduce BP. Reduced antihypertensive effects w/ sympathomimetics.
ATC Classification
C09AA08 - cilazapril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
Disclaimer: This information is independently developed by CIMS based on cilazapril from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in