Generic Medicine Info
Should be taken with food.
Hypersensitivity to aspirin or other NSAIDs, treatment of perioperative pain in the setting of CABG surgery. Severe renal impairment. 3rd trimester of pregnancy, and lactation.
Special Precautions
Patient w/ known CV disease or risk factors for CV disease, history of upper GI disease, low pretreatment of Hb concentration. Hepatic and mild to moderate renal impairment. Elderly (avoid chornic use). Patient Counselling May impair ability to perform activities requiring mental alertness or physical coordination (e.g. driving a motor vehicle, operating machinery). Monitoring Parameters Monitor CBC, liver enzymes; monitor urine output and BUN/serum creatinine in patients receiving diuretics; BP in patients receiving antihypertensives; audiogram in patients w/ baseline hearing impairment.
Adverse Reactions
Dyspepsia, nausea, constipation, vomiting, abdominal pain, diarrhoea, headache, somnolence, dizziness, tremor, confusion, increased sweating, pruritus, rash, tinnitus, blurred vision, decreased hearing, palpitations, tachycardia, ECG changes, nervousness, asthenia, peripheral oedema, dyspnoea, dysuria, cystitis, haematuria, nephrotic syndrome, upper resp infection, nasopharyngitis. Elevations in BUN, serum creatinine, serum aminotransferase concentrations, LDH and alkaline phosphatase.
Potentially Fatal: Serious CV thrombotic events, MI, stroke, renal failure, bleeding, ulceration or perforation of stomach and intestines, jaundice, cholestatic hepatitis.
ROUTE(S) : PO: C prior to 30 weeks gestation
ROUTE(S) : PO: D starting at 30 weeks gestation
Drug Interactions
Increased risk of GI bleeding w/ anticoagulants, bisphosphonates, clopidogrel, oral corticosteroids, dabigatran, rivaroxaban, salicylates and SSRIs. May reduce antihypertensive effect of ACE inhibitors. Increased nephrotoxicity w/ ciclosporin. Decreased plasma half-life w/ phenobarbital. May reduce the natriuretic effects of loop and thiazide diuretics. May increase toxicity of lithium and methotrexate. Increased risk of CNS stimulation and seizures w/ quinolones.
ATC Classification
M01AE04 - fenoprofen ; Belongs to the class of propionic acid derivatives of non-steroidal antiinflammatory and antirheumatic products.
Disclaimer: This information is independently developed by CIMS based on fenoprofen from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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