Flutamide


Concise Prescribing Info
Indications/Uses
Palliation of prostatic carcinoma.
Dosage/Direction for Use
Adult: PO 250 mg 3 times/day.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity, severe hepatic impairment, pregnancy and lactation.
Special Precautions
Perform liver function tests before starting treatment and at regular intervals. Treatment is not recommended in patients whose ALT values exceed twice the upper limit of normal. Regular assessment of prostate specific antigen level may help to monitor disease progression. Advise patient against discontinuing drug on their own. Exercise caution in patients with cardiac disease.
Adverse Reactions
Hot flushes, loss of libido, impotence, gynaecomastia, nausea, vomiting, diarrhoea, increased appetite, sleep disturbances, skin reactions, anaemias, headache, dizziness, malaise, anxiety, hypertension, gastric and chest pain, oedema, blurred vision, hepatitis, jaundice, rash, thirst, pruritus, SLE-like syndrome, drowsiness, confusion, depression, nervousness.
Drug Interactions
Increased prothrombin time in patients on long-term warfarin treatment.
ATC Classification
L02BB01 - flutamide ; Belongs to the class of anti-androgens.
Disclaimer: This information is independently developed by CIMS based on flutamide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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