Iodine


Generic Medicine Info
Contraindications
Hypersensitivity. Hypocomplementaemic vasculitis, dermatitis herpetiformis, nodular thyroid conditions with cardiac disease. Topical: Neonates, pregnancy and lactation; concomitant lithium therapy. Renal failure (K iodate tab).
Special Precautions
Patient with current or history of thyrotoxicosis, nodular goitre or latent Graves' disease, adrenal insufficiency (e.g. Addison's disease), acute bronchitis, tuberculosis, myotonia congenita, cardiac disease, acute dehydration, heat cramp. Not recommended for long term treatment. Avoid applying to large areas of the body or covering affected area with occlusive dressings (topical). Renal impairment. Children. Pregnancy and lactation. Monitoring Parameters Monitor thyroid function tests especially in pregnant women, children and neonates. Assess for signs and symptoms of hyperthyroidism.
Adverse Reactions
Significant: Thyroid-related reactions (e.g. iodine-induced hypo- or hyper-thyroidism, thyroiditis, thyroid enlargement); iodism or chronic iodine poisoning (prolonged treatment); hypersensitivity reactions (e.g. urticaria, angioedema, cutaneous haemorrhage or purpura); acne flare-ups, dermatitis. Blood and lymphatic system disorders: Lymphadenopathy, eosinophilia. Cardiac disorders: Cardiac arrhythmia. Eye disorders: Lacrimation, conjunctivitis. Gastrointestinal disorders: Nausea, vomiting, diarrhoea, increased salivation, salivary gland swelling or tenderness, stomach pain. General disorders and administration site conditions: Fever, oedema, pain or burning sensation, fatigue, influenza-like illness. Musculoskeletal and connective tissue disorders: Arthralgia. Nervous system disorders: Headache, metallic taste, numbness, tingling sensation. Psychiatric disorders: Insomnia, depression, confusion, nervousness. Reproductive system and breast disorders: Impotence, erectile dysfunction. Respiratory, thoracic and mediastinal disorders: Laryngitis, bronchitis, coryza-like symptoms. Skin and subcutaneous tissue disorders: Rash, iodine burns, myxoedema.
Drug Interactions
May cause additive hypothyroid and goitrogenic effects of lithium carbonate, iodides and amiodarone. May increase risk of hyperkalaemia with K-sparing diuretics (e.g. amiloride, triamterene), angiotensin II receptor antagonist, ACE inhibitors (e.g. captopril, enalapril); aliskiren, nicorandil, heparin. May enhance cardiac effect of quinidine.
ATC Classification
D08AG03 - iodine ; Belongs to the class of iodine product antiseptics. Used in the treatment of dermatological diseases.
Disclaimer: This information is independently developed by CIMS based on iodine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in