Generic Medicine Info
Hypersensitivity. Gout, metabolic acidosis, severe dehydration. Renal and severe hepatic impairment. Concomitant use w/ sulfonamides or alkalinising agents.
Special Precautions
Patient w/ indwelling urinary catheters; conditions wherein urine acidification is contraindicated or unattainable (e.g. presence of urea-splitting bacteria in the urine). Mild to moderate hepatic impairment. Childn. Pregnancy and lactation. Not intended for use in upper UTI. Monitoring Parameters Monitor urinalysis, urine culture, LFT. Maintain an acidic urine, or give supplemental acidification (e.g. ammonium Cl, ascorbic acid, methionine), if necessary.
Adverse Reactions
Significant: Increased ALT/AST, dysuria. GI: Dyspepsia, nausea, vomiting, diarrhoea. Genitourinary: Bladder irritation, painful/frequent micturition, albuminuria, haematuria. Dermatologic: Rash, pruritus.
Drug Interactions
Acetazolamide may inhibit conversion of methenamine into formaldehyde.
CIMS Class
ATC Classification
J01XX05 - methenamine ; Belongs to the class of other antibacterials. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on methenamine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
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