Methyltestosterone


Generic Medicine Info
Contraindications
Men with breast cancer, known or suspected prostate cancer. Pregnancy.
Special Precautions
Patient with CV disease, benign prostatic hyperplasia, chronic lung disease; obesity. Renal and hepatic impairment. Lactation. Monitoring Parameters Monitor LFTs, lipid profile, haemoglobin and haematocrit (at 3-6 months and annually thereafter); urine, and serum Ca. Monitor serum glucose in diabetic patients; prostate specific antigen if clinically indicated. Assess for signs of virilisation in women. Perform radiologic examination of the wrist and hand for prepubertal patients every 6 months.
Adverse Reactions
Significant: Peliosis hepatis, hepatic neoplasms, hepatocellular carcinoma, cholestatic hepatitis, jaundice, MI, stroke, DVT, pulmonary embolism, polycythaemia, oligospermia, reduced ejaculatory volume, priapism, benign prostatic hypertrophy, sleep apnoea. Blood and lymphatic system disorders: Clotting factors suppression. Endocrine disorders: Hirsutism. Gastrointestinal disorders: Nausea, vomiting. Immune system disorders: Anaphylactic reactions. Investigations: Change in libido. Metabolism and nutrition disorders: Hypercholesterolaemia. Nervous system disorders: Headache, paraesthesia. Psychiatric disorders: Depression, anxiety. Reproductive system and breast disorders: Amenorrhoea, impotence, mastalgia, testicular atrophy. Skin and subcutaneous tissue disorders: Acne vulgaris, androgenetic alopecia.
Drug Interactions
Enhanced effect of anticoagulants and hypoglycaemic agent. Increased hepatotoxicity of ciclosporin. Increased plasma concentrations of oxyphenbutazone.
ATC Classification
G03EK01 - methyltestosterone ; Belongs to the class of androgens and female sex hormones in combination.
G03BA02 - methyltestosterone ; Belongs to the class of 3-oxoandrosten (4) derivative androgens used in androgenic hormone preparations.
Disclaimer: This information is independently developed by CIMS based on methyltestosterone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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