Generic Medicine Info
May be taken with or without food.
Hypersensitivity. Coronary artery disease (e.g. angina pectoris, silent ischaemia, MI), coronary artery vasospasm, Prinzmetal's angina, uncontrolled HTN, cerebrovascular syndromes (e.g. stroke, TIA), hemiplegic or basilar migraine, Wolff-Parkinson-White syndrome, peripheral vascular disease, ischemic bowel disease. Severe renal (CrCl <15 mL/min) and hepatic (Child-Pugh class C) impairment. Concomitant use w/ ergot derivatives and 5-HT1 receptor agonists.
Special Precautions
Patient w/ multiple CV risk factors. Not intended for cluster headache and for the prevention of migraine attacks. Mild to moderate renal and hepatic impairment. Pregnancy and lactation. Patient Counselling This drug may cause dizziness, weakness, or drowsiness, if affected, do not drive or operate machinery. Monitoring Parameters Assess clear diagnosis of migraine and neurological conditions prior to initiation of therapy. Perform periodic CV evaluation for patients w/ risk factors for coronary artery disease who are receiving intermittent long-term therapy. Monitor ECG, BP, signs and symptoms of withdrawal, serotonin syndrome, angina, hypersensitivity reactions, and headache severity.
Adverse Reactions
Significant: Chest pain/tightness, peripheral vascular ischaemia, GI vascular ischaemia/infarction, splenic infarction, Raynauld's syndrome, transient and permanent blindness, partial loss of vision, recurrent/rebound headaches, withdrawal syndrome; hypertensive crisis, medication-overuse headache (MOH). Nervous: Tingling sensation, paraesthesia, dizziness, somnolence, drowsiness, malaise, fatigue, heaviness sensation, hot/cold flushes, dizziness, vertigo, weakness. CV: Bradycardia, palpitations. GI: Nausea, vomiting, xerostomia. Resp: Pharynx constriction. Musculoskeletal: Neck pain. Ophthalmologic: Photophobia.
Potentially Fatal: Acute MI, coronary artery vasospasm, transient ischaemia, ventricular tachycardia/fibrillation, cerebral or subarachnoid haemorrhage, stroke, hypersensitivity reactions (e.g. angioedema).
CIMS Class
Antimigraine Preparations
ATC Classification
N02CC02 - naratriptan ; Belongs to the class of selective serotonin (5HT1) agonists preparations. Used to relieve migraine.
Disclaimer: This information is independently developed by CIMS based on naratriptan from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 CIMS. All rights reserved. Powered by
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