Oxybutynin


Concise Prescribing Info
Indications/Uses
Overactive bladder.
Dosage/Direction for Use
Adult: PO 2.5-5 mg 2-3 times/day. Max: 5 mg 4 times/day if needed. Extended-release Initial: 5 mg once daily, increase slowly if needed. Max 30 mg/day. Transdermal Per patch delivering 3.9 mg/day: Apply 1 patch to abdomen, hip or buttock twice wkly.
Administration
May be taken with or without food.
Contraindications
GI obstruction or atrophy, severe toxic megacolon, significant bladder outflow obstruction, glaucoma, urinary retention.
Special Precautions
Elderly; hepatic or renal impairment; neuropathy; hyperthyroidism; prostatic hyperplasia; hiatus hernia; cardiac disease, reflux oesophagitis, ulcerative colitis, myasthenia gravis; pregnancy and lactation. High environmental temperature might cause heat prostration (fever with heat stroke due to decreased sweating).
Adverse Reactions
Dry mouth, constipation, nausea, abdominal pain; blurred vision; headache, dizziness, drowsiness; dry skin, rash; photosensitivity, diarrhoea, insomnia, palpitation, weakness, dry eyes, confusion, hypertension, UTI, dyspepsia.
Drug Interactions
Co-administration with other anticholinergic drugs may cause undesirable increased anticholinergic effects. Additive sedation with CNS depressants and alcohol. Concentration may be increased by CYP3A4 inhibitirs (e.g. imidazole antifungals, macrolide antibiotics).
ATC Classification
G04BD04 - oxybutynin ; Belongs to the class of urinary antispasmodics.
Disclaimer: This information is independently developed by CIMS based on oxybutynin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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