Reboxetine


Concise Prescribing Info
Indications/Uses
Depression.
Dosage/Direction for Use
Adult: PO 4 mg twice daily, then up to 10 mg/day after 3-4 wk if needed. Max: 12 mg/day.
Administration
May be taken with or without food.
Special Precautions
Renal and hepatic impairment, benign prostatic hyperplasia, cardiac disorders, epilepsy, bipolar disorders, urinary retention, glaucoma. May impair ability to perform tasks requiring mental alertness, driving or operating machinery. Monitor for signs of clinical worsening eg. suicidal tendency especially during the initial phase of the treatment.
Adverse Reactions
Insomnia, dizziness, increased sweating, impotence, dry mouth, constipation, urinary hesitancy, dry mouth, postural hypotension, dysuria, paraesthesia, hyponatraemia, tachycardia.
Potentially Fatal: Tachycardia.
Drug Interactions
Avoid concomitant admin with antiarrhythmics, antipsychotics, ciclosporin, imidazole and triazole antifungals, TCAs. Concurrent use with CYP3A4 inhibitors may increase plasma levels of reboxetine. Concurrent use with ergot derivatives may increase BP.
CIMS Class
ATC Classification
N06AX18 - reboxetine ; Belongs to the class of other antidepressants.
Disclaimer: This information is independently developed by CIMS based on reboxetine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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