Acifar

Acifar

aciclovir

Manufacturer:

Ifars
Concise Prescribing Info
Contents
Acyclovir
Indications/Uses
Treatment of herpes simplex infections in skin & mucous membrane, including initial & recurrent genital herpes. Prevention of recurrent herpes simplex infections in immunocompetent patients. Prophylaxis of herpes simplex in immunocompromised patients. Treatment of herpes zoster.
Dosage/Direction for Use
Adult Herpes simplex 200 mg 5 times daily 4 hrly w/o night dose for 5 days, may be increased to 400 mg daily. Suppression of herpes simplex in immunocompetent patient 200 mg 4 times daily 6 hrly. Prophylaxis of herpes simplex in immunocompromised patient 200 mg 4 times daily 6 hrly. Doses may be increased to 400 mg in severe immunocompromised patients (post-bone marrow transplant) or indigestion. Herpes zoster 800 mg 5 times daily 4 hrly w/o night dose for 5 days. Childn Treatment & prophylaxis of herpes simplex in immunocompromised patient Childn ≥2 yr Adult dose, <2 yr ½ adult dose. Severe renal dysfunction (CrCl 10 mL/min) 200 mg twice daily 12 hrly. Herpes zoster in patient w/ severe renal dysfunction 800 mg twice daily 12 hrly. Herpes zoster in patient w/ moderate renal dysfunction (CrCl 10-25 mL/min) 800 mg 3 times daily.
Administration
May be taken with or without food: May be taken w/ meals to reduce GI discomfort.
Contraindications
Hypersensitivity.
Special Precautions
Renal dysfunction. Pregnancy & lactation. Elderly w/ CrCl disturbance.
Adverse Reactions
Skin rash, reversible neurological reactions, GI disturbances, increased bilirubin & liver enzymes, increased BUN & creatinine, lowering of haematological index, headache & fatigue.
Drug Interactions
Increased t½ w/ probenecid.
MIMS Class
ATC Classification
J05AB01 - aciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.
Presentation/Packing
Form
Acifar caplet 200 mg
Packing/Price
10 × 10's (Rp107,316/boks)
Form
Acifar caplet 400 mg
Packing/Price
3 × 10's (Rp58,311/boks)
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