Caprenem

Caprenem

meropenem

Manufacturer:

Caprifarmindo
Concise Prescribing Info
Contents
Meropenem
Indications/Uses
Pneumonia, UTI, gynecological infections eg, endometritis, skin & skin structure infections. Nosocomial pneumonia, peritonitis, septicemia, presumed infections in neutropenic patient. Meningitis.
Dosage/Direction for Use
Adult Pneumonia, UTI, gynecological infections eg, endometritis, skin & skin structure infections 500 mg IV 8 hrly. Nosocomial pneumonia, peritonitis, septicemia, presumed infections in neutropenic patients 1 g IV 8 hrly. Meningitis 2 g IV 8 hrly. Renal impairment: CrCl 26-50 mL/min 1 unit dose 12 hrly, 10-25 mL/min ½-1 unit dose 12 hrly, <10 mL/min ½-1 unit dose 24 hrly. Childn >3 mth up to 12 yr 10-20 mg/kg 8 hrly depending on type & severity of infection, susceptibility of the pathogen & condition of the patient. >50 kg Same as adult dose. Meningitis 40 mg/kg 8 hrly.
Contraindications
Hypersensitivity.
Special Precautions
Hypersensitivity to β-lactams. Do not use for infections due to MRSA. Monitor serum hepatic levels in patients w/ hepatic disease. Consider diagnosis of pseudomembranous colitis in patients who develop diarrhea. May impair ability to drive & operate machinery. Pregnancy & lactation. Infant <3 mth.
Adverse Reactions
Inflammation, thrombophlebitis, inj site pain; pruritic rash, urticaria; abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis; reversible thrombocythemia, eosinophilia, thrombocytopenia, leucopenia, neutropenia; increased serum conc eg, bilirubin, transaminases, alkaline phosphatase & lactic dehydrogenase alone or combination; headache, paresthesia, convulsion; oral & vag candidosis.
Drug Interactions
Probenecid; other nephrotoxic drugs.
MIMS Class
ATC Classification
J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.
Presentation/Packing
Form
Caprenem powd for inj 1 g
Packing/Price
1's (Rp463,100/boks)
Form
Caprenem powd for inj 0.5 g
Packing/Price
1's (Rp243,800/boks)
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