Coveram

Coveram

perindopril + amlodipine

Manufacturer:

Servier
Concise Prescribing Info
Contents
Perindopril arginine, amlodipine besylate
Indications/Uses
Substitution therapy in patients w/ essential HTN &/or stable CAD controlled w/ perindopril & amlodipine.
Dosage/Direction for Use
Administration
Should be taken on an empty stomach: Take before a meal, preferably in the morning.
Contraindications
Hypersensitivity. Angioedema associated w/ previous ACE inhibitor therapy, severe hypotension, cardiogenic shock, unstable angina pectoris (excluding Prinzmetal's angina), heart failure after acute MI. 2nd & 3rd semester of pregnancy.
Special Precautions
Hypotension, hypertrophic cardiomyopathy, cardiac failure, surgery, impaired hepatic function, hepatic failure, renal impairment.
Adverse Reactions
Dizziness, headache, abdominal pain, nausea, vertigo, palpitations, flushing, fatigue, asthenia.
Drug Interactions
K-sparing diuretics, K supplements, lithium, NSAID, insulin, hypoglycemic sulfonamides, sympathomimetics, dantrolene, CYP3A4 inducers eg, rifampicin, Hypericum perforatum, anticonvulsant, CYP3A4 inhibitors eg, itraconazole, ketoconazole.
ATC Classification
C09BB04 - perindopril and amlodipine ; Belongs to the class of ACE inhibitors and calcium channel blockers. Used in the treatment of cardiovascular diseases.
Presentation/Packing
Form
Coveram 5 mg/5 mg tab
Packing/Price
30's (Rp323,400/blister)
Form
Coveram 10 mg/10 mg tab
Packing/Price
30's (Rp444,700/blister)
Form
Coveram 10 mg/5 mg tab
Packing/Price
30's (Rp444,700/blister)
Form
Coveram 5 mg/10 mg tab
Packing/Price
30's (Rp323,400/blister)
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