Tab/InfusionAdultCryptococcal meningitis Initially 400 mg, then 200-400 mg once daily. Candidemia & other systemic candidal infections Initially 400 mg, then 200 mg daily which may be increased to 400 mg daily. Systemic candidal/cryptococcal infectionChildn>4 wk 6-12 mg/kg once daily. Neonate 2-4 wk 6-12 mg/kg 48 hrly, <2 wk 6-12 mg/kg 72 hrly.
May be taken with or without food.
Hypersensitivity to fluconazole or triazole.
Monitor liver function during treatment. Discontinue in bullous lesion or erythema multiforme. Monitor blood glucose level & prothrombin time in patients receiving coumarin anticoagulants. Pregnancy & lactation. Childn.