Not for use as an as needed analgesic, management of acute or post-op pain. Hypotension. Discontinue if paralytic ileus is suspected. Patients w/ substantially decreased resp reserve or pre-existing resp depression, COPD; head injuries; chronic constipation; inflammatory or obstructive bowel disorders; acute pancreatitis secondary to biliary disease; about to undergo biliary surgery; adrenocortical insufficiency, myxedema, hypothyroidism, prostatic hypertrophy or urethral stricture. CNS depression, kyphoscoliosis, toxic psychosis, acute alcoholism, delirium tremens, convulsive disorders. Patients scheduled for regional anesth procedures or other interruptions of pain transmission pathways. Concomitant use w/ CNS depressants; follow patients closely for signs of resp depression & sedation. Not to be abruptly discontinued. Patients w/ rare hereditary problems of galactose intolerance, the Lapp deficiency or glucose-galactose malabsorption. Contains Na metabisulfite which may cause allergic-type reactions. Evaluate patients ongoing basis for onset of a new sleep apnea or worsening of existing sleep apnea. Monitor patients for signs of abuse, misuse or addiction. May impair ability to drive & operate machinery. Renal insufficiency or mild to moderate hepatic insufficiency. Not to be used during pregnancy & labor. Not to be used during breastfeeding. Elderly.
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