Nomika

Nomika

minocycline

Manufacturer:

Ikapharmindo
Concise Prescribing Info
Contents
Minocycline HCl
Indications/Uses
Infections caused by rickettsia, pneumonial mycoplasma, psittacosis & ornithosis, lymphogranuloma venereum & granuloma inguinal, relapsing fever; gm +ve & gm -ve bacteria resistant to other tetracyclines. Uncomplicated gonococcal urethritis in men. Adjunct in acute intestinal amoebiasis; severe acne.
Dosage/Direction for Use
Adult Initially 200 mg then 100 mg every 12 hr. Childn >8 yr Initially 4 mg/kg then 2 mg/kg  every 12 hr. Gonorrhea in penicillin-sensitive patients Initially 200 mg then 100 mg every 12 hr. Min of 4 days w/ 2-3 days post-therapy culture. Meningococcal carrier 100 mg 12 hrly for 5 days. Mycobacterium marinum infections 100 mg twice daily for 6-8 wk. Uncomplicated gonococcal urethritis in male 100 mg twice daily for 5 days. Duration of treatment: Syphilis 10-15 days.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. SLE. Severe renal impairment. Pregnancy & lactation. Childn <12 yr. Neonates.
Special Precautions
Use in patient w/ kidney failure & neonate may cause enamel hypoplasia; discoloration of teeth during tooth growth stage. Discontinue in case of superinfection. Periodically monitor organ systems during long-term use.
Adverse Reactions
Hypersensitivity reactions; GI & CNS effects; maculopapular rash, erythema, skin & mucous membrane pigmentation; hemolytic anemia, thrombocytopenia, neutropenia, eosinophilia; pseudo-cerebral tumor in adults, bulging fontanels in infants, headache.
Drug Interactions
Tetracycline enhance methoxyflurane-induced nephrotoxicity. Inhibition in digestive tract w/ Na bicarbonate. Inhibition of oral absorption w/ antacids containing divalent & trivalent cations & Fe prep. Interferes w/ penicillins. Reduced plasma prothrombin activity of vit K.
ATC Classification
J01AA08 - minocycline ; Belongs to the class of tetracyclines. Used in the systemic treatment of infections.
Presentation/Packing
Form
Nomika cap 50 mg
Packing/Price
10 × 10's (Rp525,000/boks)
Form
Nomika cap 100 mg
Packing/Price
10 × 10's (Rp1,017,000/boks)
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