Post-op nausea & vomiting
Initially 8 mg orally 1 hr before anesth, followed by two 8-mg oral doses 8 hrly. Prevention of chemotherapy-induced nausea & vomiting Adult
Highly emetogenic chemotherapy: Initially 8 mg by slow IV infusion or 15-min infusion immediately before chemotherapy, then continuous IV infusion of 1 mg/hr for up to 24 hr or 2 inj of 8 mg by slow IV inj or 15-min infusion 4 hr apart, or followed by 8 mg orally twice daily for up to 5 days. Radiotherapy-induced nausea & vomiting
8 mg orally 3 times daily, 1st dose should be taken 1-2 hr before radiotherapy. Childn
5 mg/mL IV 15 min before chemotherapy, then 4 mg orally 12 hrly for up to 5 days. Impaired liver function
Total daily dose should not be >8 mg.