Adult & childn ≥30 kg or >12 yr 50-100 mg twice daily. May be increased to 200 mg twice daily for more severe or intractable infections. Uncomplicated gonorrhoea 400 mg single dose. Childn <30 kg 1.5-3 mg/kg/day in divided doses twice daily. May be increased to 6 mg/kg twice daily for more severe or intractable infections.
Hypersensitivity to penicillins; personal or familial history of some forms of allergies eg, bronchial asthma, rash or urticaria. Impaired renal function, patients w/ poor oral nutrition, patients receiving parenteral nutrition. History of GI disease, particularly colitis. Prolonged treatment may result in superinfection. Pregnancy & lactation. Childn <6 mth. Elderly or debilitated patients.