May gradually change eye colour, darken eyelid & increase length, thickness, pigmentation &/or number of eyelashes. Periorbital & lid changes eg, deepening of eyelid sulcus. Patient w/ active intraocular inflammation, known predisposing risk factors for iritis/uveitis. Aphakic patients, pseudophakic patients w/ a torn posterior lens capsule or anterior chamber lenses or w/ known risk factors for cystoid macular edema. Avoid skin contact. May cause skin irritation & reactions. Pregnancy & lactation. Childn <18 yr.