Zypraz

Zypraz

alprazolam

Manufacturer:

Kalbe Farma
Concise Prescribing Info
Contents
Alprazolam
Indications/Uses
Anxiety, panic disorders w/ or w/o agoraphobia.
Dosage/Direction for Use
Anxiety 0.25-0.5 mg 3 times daily. Max: 4 mg daily in divided doses. Panic disorders Initially 0.5-1 mg at bedtime or 0.5 mg 3 times daily. May increase to 1 mg daily for 3-4 days. Elderly or debilitated patient; severe hepatic dysfunction 0.25 mg 2-3 times daily.
Administration
May be taken with or without food: Side effects eg, sleepiness/drowsiness may be reduced if taken immediately after meals.
Contraindications
Acute narrow-angle glaucoma, myasthenia gravis, acute pulmonary insufficiency, phobia & chronic psychotic obsessive conditions. Childn & premature infants.
Special Precautions
W/drawal syndrome, depression or neurotic depression. Chronic hepatic, renal or pulmonary disease, muscle weakness, a history of drug or alcohol abuse, marked personality disorders. Long-term therapy. May affect ability to drive or operate machinery. Pregnancy & lactation.
Adverse Reactions
Drowsiness, dizziness, ataxia, amnesia, confusion, hallucination, blurred vision, headache, insomnia, tremor, hypotension, GI disorders, skin rash, change in libido, menstrual irregularities, urinary retention, blood dyscrasias, jaundice.
Drug Interactions
Effect enhanced by CNS depressants, alcohol, barbiturates. Cimetidine & fluvoxamine may affect metabolism of alprazolam. Avoid concomitant administration w/ azole antifungals.
MIMS Class
ATC Classification
N05BA12 - alprazolam ; Belongs to the class of benzodiazepine derivatives anxiolytics. Used in the management of anxiety, agitation or tension.
Presentation/Packing
Form
Zypraz tab 0.5 mg
Packing/Price
5 × 10's (Rp133,750/boks)
Form
Zypraz tab 1 mg
Packing/Price
5 × 10's (Rp209,300/boks)
Form
Zypraz tab 0.25 mg
Packing/Price
5 × 10's (Rp71,500/boks)
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