Avosoda

Avosoda

Manufacturer:

Abio

Distributor:

Apex
Concise Prescribing Info
Contents
Per 4 g Na bicarbonate 1.76 g, Na citrate 0.63 g, anhydrous citric acid 0.72 g, tartaric acid 0.89 g
Indications/Uses
Urinary alkalinization; treatment of mild UTI; symptomatic relief of dysuria & gastric hyperacidity; adjuvant in gout treatment w/ uricosurics & allopurinol, enhance action of certain antibiotics especially sulfonamides.
Dosage/Direction for Use
4-8 g bd-tds.
Administration
May be taken with or without food: Dissolve in 200 mL of water. Drink after the effervescence has settled down to avoid eructation.
Contraindications
Severe renal impairment & associated oliguria, azotaemia or anuria, untreated Addison's disease, acute dehydration; heat cramps & severe myocardial damage. Concomitant use w/ urinary tract antiseptics that require acid urine eg, methenamine, mandelate & methenamine hippurate.
Special Precautions
Peptic ulcer, renal abnormalities, metabolic alkalosis. Not to be taken on Na-restricted diet. Pregnancy & lactation.
Adverse Reactions
Na overload & hyperosmolarity; large doses may lead to GI events eg, diarrhea, nausea & vomiting, & laxative effects.
Drug Interactions
Systemic alkalosis, promoted development of Ca stones & cause hypernatraemia w/ antacids. Increased Al absorption possibly resulting in acute Al toxicity w/ Al-containing antacids. Reduced solubility of quinolones in urine w/ citrates; patients should be observed for signs of crystalluria & nephrotoxicity. Increased urinary excretion & decreased therapeutic effects of salicylates.
ATC Classification
B05CB02 - sodium citrate ; Belongs to the class of salt solutions used as irrigating solutions.
Presentation/Packing
Form
Avosoda effervescent granules
Packing/Price
4 g x 1's
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