View Bonviva overdosage for action to be taken in the event of an overdose.
Administration
Should be taken on an empty stomach: Take at least 1 hr before the 1st food/drink/medication of the day w/ a full glass of plain water & remain in sitting/upright position for at least 1 hr. Swallow whole, do not chew/crush/suck.
Contraindications
Hypersensitivity. Esophageal abnormalities eg, stricture or achalasia, uncorrected hypocalcemia, inability to stand or sit upright for at least 60 min.
Active upper GI problems (eg, Barrett's esophagus, dysphagia, other esophageal diseases, gastritis, duodenitis or ulcers). Discontinue use in case dysphagia, odynophagia, retrosternal pain or new or worsening heartburn occur. Osteonecrosis of the jaw; dental surgery. Correct hypocalcemia & other bone & mineral metabolism disturbances prior to treatment. Concomitant use w/ NSAIDs. Severe renal impairment. Not to be used during pregnancy & lactation. Childn <18 yr.
Interfered absorption w/ Ca-, Al-, Mg-, Fe-containing products including milk & food. Increased bioavailability w/ IV ranitidine. Concomitant use of aspirin or NSAIDs.
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