Chlormethine


Concise Prescribing Info
Indications/Uses
Mycosis fungoides.
Dosage/Direction for Use
Adult : Topical Apply a thin film once daily.
Dosage Details
Topical/Cutaneous
Mycosis fungoides
Adult: Apply a thin film once daily to the affected area.
Special Precautions
Pregnancy and lactation.
Adverse Reactions
Immune system disorders: Hypersensitivity.
Skin and subcutaneous tissue disorders: Dermatitis, skin infections, pruritus, skin ulceration, skin blister, hyperpigmentation.
Intracavitary/IV/Parenteral/Topical: D
Patient Counseling Information
Avoid any contact with mucous membranes.
MonitoringParameters
Monitor for hypersensitivity and skin reactions.
Action
Description: Chlormethine is a bifunctional alkylating agent that inhibits rapidly proliferating cells.
Chemical Structure

Chemical Structure Image
Chlormethine

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 4033, Mechlorethamine. https://pubchem.ncbi.nlm.nih.gov/compound/Mechlorethamine. Accessed Sept. 24, 2020.

Storage
Unopened tubes: Store between -15 to - 25°C. After defrosting: Store between 2-8°C.
ATC Classification
L01AA05 - chlormethine ; Belongs to the class of alkylating agents, nitrogen mustard analogues. Used in the treatment of cancer.
References
Buckingham R (ed). Chlormethine Hydrochloride. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 29/06/2020.

Joint Formulary Committee. Chlormethine. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 29/06/2020.

Disclaimer: This information is independently developed by MIMS based on Chlormethine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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